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Clear Cell Renal Cell Carcinoma Metastasized By A Breast Ductal Carcinoma.
Autor: M. Urdiales-viedma, R. J. Luque, F. Valle Y S. Martos-padilla.
Editorial: Archivos Españoles de Urología
5 páginas
Pago único: €6.20
Requiere suscripción: Académico
Tipo de publicación: Articulo
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OBJECTIVE: To report a clear cell renal cell carcinoma recipient of a metastasizing ductal carcinoma of the breast: A tumor-to-tumor metastasis.

METHODS: A 71 year-old woman with a past history of breast carcinoma, diagnosed 12 years before, underwent a nephrectomy for an incidental kidney mass found in a routine imaging examination.

RESULTS: Histological examination revealed foci of ductal carcinoma of the breast in an otherwise typical clear cell renal cell carcinoma of the kidney. Immunohistochemical examination confirmed a metastasis of an infiltrating breast carcinoma to a clear cell renal cell carcinoma (positive to GATA3, hormonal receptors and mamoglobin) in a clear cell renal cell carcinoma (positive to PAX8, CD10 and vimentin).

CONCLUSIONS: Awareness of this phenomenon should always be kept in mind by urologist in patients with a known history of a previous malignancy and by pathologists when finding a renal tumor with an unusual or dimorphic morphology. Immunohistochemistry plays an important role to establish the exact diagnosis.


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Revista Internacional de Urología indexada y peer-reviewed, fundada en 1944, dirigida a toda la comunidad científica. Aquí encontrarás las últimas novedades y hallazgos urológicos. Publicamos 10 números anuales.